An Area- and Energy-Efficient 16-Channel, AC-Coupled Neural Recording Analog Frontend for High-Density Multichannel Neural Recordings

We present an AC-coupled modular 16-channel analog frontend with 1.774 fJ/c-s?mm2 energy- and area-product for a multichannel recording of broadband neural signals including local field potentials (LFPs) extracellular action (EAPs). To achieve such small area- energy-product, we employed operational transconductance amplifier (OTA) positive feedback, instead widely-used folded cascode OTA (FC-OTA) or current mirror conventional recordings, while optimizing the design parameters affecting performance, power, area trade-offs. In addition, second pole was strategically introduced in LNA to reduce noise bandwidth without in-channel low-pass filter. Compared works, presented method shows better performance terms noise, usages. The fabricated is fully characterized benchtop vitro setup. embraces LFPs EAPs 4.27 ?Vrms input referred (0.5–10 kHz) 53.17 dB dynamic range, consuming 3.44 ?W 0.012 mm2 per channel. channel figure merit (FoM) prototype 147.87 fJ/c-s energy-area FoM (E-A FoM) fJ/c-s?mm2.